PVM nutrient-permeable channel but not protein export is impaired in ΔEXP1 parasites. (A) IFA images of control and ΔEXP1 parasites (rapalog) probed with α-HA (EXP1*-HA) and α-KAHRP. (B) Live cell imaging of control and ΔEXP1 parasites (rapalog) expressing SBP1-mScarlet.
Mesén-Ramírez P, Bergmann B, Tran TT, Garten M, Stäcker J, Naranjo-Prado I, Höhn K, Zimmerberg J, Spielmann T. EXP1 is critical for nutrient uptake across the parasitophorous vacuole membrane of malaria parasites. PLoS Biol. 2019 17(9):e3000473.
PubMed Article: EXP1 is critical for nutrient uptake across the parasitophorous vacuole membrane of malaria parasites
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0202000 | knob-associated histidine-rich protein |
PF3D7_0501300 | skeleton-binding protein 1 |