Localization of dematin in P. falciparum iRBC. B) CLSM observations of normal human RBCs (a) and erythrocytes infected by P. falciparum at different developmental stages: trophozoite (b), schizont (c), gametocyte (d), stained with the a-EXP1 serum (green), which decorate the PVM, and a-dematin md52k serum (red). Dematin is an RBC membrane associated protein. Nuclei were stained with DAPI (blue). Displayed micrographs correspond to a single stack encompassing the center of the nucleus. T, transmission light acquisition. Scale bars, 1 mm.

Lalle M, Curra C, Ciccarone F, Pace T, Cecchetti S, Fantozzi L, Ay B, Braun Breton C, Ponzi M. Dematin, a component of the erythrocyte membrane-skeleton, is internalized by the malaria parasite and associates with Plasmodium 14-3-3. J Biol Chem. 2010. 286:1227-36