Boxed regions are numbered and depicted in higher magnification to the right. The nucleus is stained with DAPI (blue). f) PF10_0348-GFP (green) localized to the surface of schizonts and free merozoites in unfixed parasites. g) PF10_0348-GFP co-localized with the surface protein MSP-1 (red) in fixed parasites. Dynamics of MAL13P1.130-GFP (green) during schizogony in unfixed parasites. In early schizogony (T1), MAL13P1.130-GFP emerged as a cramp-like-structure at the apical tip of forming merozoites (h). This structure develops to be ring-like (T2) before becoming evenly distributed at the periphery of the nascent merozoite (T3-4). The third row shows a schematic representation. For confocal three-dimensional reconstitution,
Hu G, Cabrera A, Kono M, Mok S, Chaal BK, Haase S, Engelberg K, Cheemadan S, Spielmann T, Preiser PR, Gilberger TW, Bozdech Z. Transcriptional profiling of growth perturbations of the human malaria parasite Plasmodium falciparum. Nature Biotechnol. 2010 28:91-8.
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0930300 | merozoite surface protein 1 |
PF3D7_1035700 | duffy binding-like merozoite surface protein |
PF3D7_1323700 | glideosome associated protein with multiple membrane spans 1 |