PF3D7_1224300 polyadenylate-binding protein 1, putative

Localization of 7-Helix-1 in stress granules (SGs) and interaction with translational repressors. Co-localization of 7-Helix-1 with CITH, PABP1 and DOZI (development of zygote inhibited). WT NF54 gametocytes were immunolabeled with mouse anti-7-Helix-1rp2 antisera (green) and rabbit anti-CITH, anti-PABP1, or anti-DOZI antibodies (red). Nuclei were highlighted by Hoechst33342 nuclear stain (blue). DIC, differential interference contrast. Bar, 5 μm. Results are representative of three independent experiments. Bennink S, von Bohl A, Ngwa CJ, Henschel L, Kuehn A, Pilch N, Weißbach T, Rosinski AN, Scheuermayer M, Repnik U, Przyborski JM, Minns AM, Orchard LM, Griffiths G, Lindner SE, Llinás M, Pradel G. A seven-helix protein constitutes stress granules crucial for regulating translation during human-to-mosquito transmission of Plasmodium falciparum. PLoS Pathog. 2018 14(8):e1007249. PMID: 30133543

Other associated proteins

PFID Formal Annotation
PF3D7_0320800 ATP-dependent RNA helicase DDX6
PF3D7_0525400 G-protein coupled receptor, putative
PF3D7_1474900 trailer hitch homolog, putative
img