Localization of PfDOC2. Confocal immunofluorescence microscopy using anti-PfDOC2 antisera. (A) PfDOC2 labeled cells were visualized with Alexa 488 (green); (B) Blue: DAPI stains the nucleus of infected cells. (C) PfDOC2 and DAPI overlay. (D) DIC: differential interference contrast. PfDOC2 is localized within the parasite in a punctate manner reminiscent of vesicles but not with the erythrocyte membrane.

Jean S, Zapata-Jenks MA, Farley JM, Tracy E, Mayer DC. Plasmodium falciparum double C2 domain protein, PfDOC2, binds to calcium when associated with membranes. Exp Parasitol. 2014 144:91-5.