PfPDEδ is a membrane-associated protein with its catalytic domain located in the parasitophorous vacuole. Immunofluorescence assay with anti-PfPDEδ and anti-Pfg27 co-labeling performed on stage V gametocytes at 0 min, 5 min, 15 min and 30 min after activation into gametes. E: Pies show the proportion of PfPDEδ-positive (red) and negative (grey) cells. N = number of cells counted in one experiment. Scale bars: 2 μm.

N'Dri ME, Tavella TA, Royer L, Dupuy F, Bedault L, Verdier F, Lavazec C. Phosphodiesterase delta governs the mechanical properties of erythrocytes infected with Plasmodium falciparum gametocytes. Microbes Infect. 2023 25(5):105102.