PfRbsn5, PfVPS45, and PfRab5b inactivation-induced vesicles are hemoglobin filled and not connected to the host cell. Microscopy images of -hemoglobin (Hemoglobin) IFAs of formaldehyde-fixed, PfVPS45endo, PfRbsn5endo, and PfRab5bendo knock-sideways (6 h rapalog) and control parasites (cell lines indicated). White arrows: accumulated hemoglobin positive signals, blue arrows: DV. Nuclei were stained with DAPI. DIC, differential interference contrast.
Scale bar, 5 μm.
Kazan MM, Asmare MM, Mahapatra RK. Identification of Potential Drug Targets in Erythrocyte Invasion Pathway of Plasmodium falciparum. Curr Microbiol. 2023 Apr 5;80(5):165. doi: 10.1007/s00284-023-03282-4. PMID: 37020052.
PubMed Article: Identification of Potential Drug Targets in Erythrocyte Invasion Pathway of Plasmodium falciparum
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0216400 | vacuolar protein sorting-associated protein 45, putative |
PF3D7_1310600 | ras-related protein Rab-5B secretory complex protein 61 alpha |