PF3D7_1323500 PEXEL protease plasmepsin V

Malaria parasites survive inside red blood cells by exporting proteins that renovate the cell. Inhibition of the export process, by blocking the malarial enzyme, Plasmepsin V, prevents red cell remodeling and kills the parasite. Sedwick C. Plasmepsin V, a secret weapon against malaria. PLoS Biol. 2014 12(7):e1001898. PMID: 24983361

img