PfSAC1-3HA is constitutively expressed throughout the asexual erythrocytic life cycle. Immunofluorescence assay using anti-HA antibody showing that PfSAC1-3HA is expressed in ring (a), trophozoite (b) and schizont (c) stages. Merge shows the HA signal in green and the Dapi stained nucleus in blue. The HA overexposed panels are to highlight the additional faint labelling around the nucleus (yellow arrows). Scale bar is 5 μm. results demonstrate that PfSAC1 is expressed throughout the asexual stages of the erythrocytic cycle, and that it is potentially found enriched at some regions of the ER.

Thériault C, Richard D. Characterization of a putative Plasmodium falciparum SAC1 phosphoinositide-phosphatase homologue potentially required for survival during the asexual erythrocytic stages. Sci Rep. 2017 Oct 5;7(1):12710