PfPNPLA2 is important for asexual blood-stage proliferation. (D) Mitochondrial morphology in WT and PfPNPLA2-KO parasites as visualized by expression of mCherry directed to the mitochondrion (Mito-mCherry, magenta). (E) Apicoplast morphology in WT and PfPNPLA2-KO parasites as visualized by the expression of mCherry directed to the apicoplast (Apico-mCherry, magenta). Nuclei were stained with DAPI (blue). DIC, differential interference contrast. All scale bars, 5 µm. Pietsch E, Ramaprasad A, Bielfeld S, Wohlfarter Y, Maco B, Niedermüller K, Wilcke L, Kloehn J, Keller MA, Soldati-Favre D, Blackman MJ, Gilberger T-W, Burda P-C. A patatin-like phospholipase is important for mitochondrial function in malaria parasites. mBio. 2023 PMID: 37882543;