Localization of PfALAD in P. falciparum by immunoelectron microscopy. A and B, localization of host ALAD in the parasite and red blood cell. C and D, localization of PfALAD in the apicoplast with multimembrane structure. The abundant presence of host ALAD in the cytoplasm and food vacuole and the sparse occurrence of PfALAD in the apicoplast (shown by the arrow) of P. falciparum is indicated by the distribution of gold particles. Scale bar = 0.5 μm. Pc, parasite cytoplasm. Rc, red cell cytoplasm. Fv, food vacuole. Ap, apicoplast. Dhanasekaran S, Chandra NR, Chandrasekhar Sagar BK, Rangarajan PN, Padmanaban G. Delta-aminolevulinic acid dehydratase from Plasmodium falciparum: indigenous versus imported. J Biol Chem. 2004;279(8):6934-42.