Distinct subcellular localization of PfSUMO conjugated proteins. A. Co-localization assays of PfSUMO antiserum with nuclear marker PfSir2, cytoplasmic marker, PfHsp70-1 and Maurer's clefts marker, Pf332 reveal compartmentalization. Size bar corresponds to 1 μm. B. Schematic. Underlined compartments have been shown to react with anti-PfSUMO antibodies. In the nucleus, PfSir2 has been identified, in this work, as the first putative SUMO target in P. falciparum. Issar N, Roux E, Mattei D, Scherf A. Identification of a novel post-translational modification in Plasmodium falciparum: protein sumoylation in different cellular compartments. Cell Microbiol. 2008. PMID: 18547337