PfPDEd is a membrane-associated protein with its catalytic domain located in the parasitophorous vacuole Immunofluorescence assay with anti-PfPDEd and anti-Pfg27 co-labeling performed on stage V gametocytes at 0 min, 5 min, 15 min and 30 min after activation into gametes .E: Pies show the proportion of PfPDEd-positive (red) and negative (grey) cells. n=number of cells counted in one experiment. Scalebars: 2 mm.

N'Dri ME, Tavella TA, Royer L, Dupuy F, Bedault L, Verdier F, Lavazec C. Phosphodiesterase delta governs the mechanical properties of erythrocytes infected with Plasmodium falciparum gametocytes. Microbes Infect. 2023 25(5):105102.