Overview of the sites of action of apicoplast-targeting drugs. IPP, isopentenyl pyrophosphate; DMAPP, dimethyallyl pyrophosphate; TPT, triosephosphate transporters; DOXP, 1-deoxy-D-xylulose-5-phosphate; FAS I, fatty acid type I synthesis, FAS II, fatty acid type II synthesis; N, nucleus; ER, endoplasmic reticulum
Biddau M, Sheiner L. Targeting the apicoplast in malaria. Biochem Soc Trans. 2019 47(4):973-983. PMID: 31383817.
PubMed Article: Targeting the apicoplast in malaria