Rep20+ plasmids physically associate with P. falciparum telomeric clusters. Smears of trophozoite-stage parasites from Rep20– pHHC* (A) and Rep20+ pHHC*/DR1.4 (B) transfected populations, prepared from day 0 cultures shown in Figure 3, were analyzed by DAPI staining and by FISH using TARE 3, and plasmid backbone probes used to detect telomeric clusters and transfected plasmid, respectively. The two rows in each panel show two different representative fields. O'Donnell RA, Freitas-Junior LH, Preiser PR, Williamson DH, Duraisingh M, McElwain TF, Scherf A, Cowman AF, Crabb BS. A genetic screen for improved plasmid segregation reveals a role for Rep20 in the interaction of Plasmodium falciparum chromosomes. EMBO J. 2002 21(5):1231-9. PMID: 11867551