Subcellular location of PfHMGB1 in transgenic ring-stage parasites detected by IFA with anti-Ty1 antibody (green). The nuclei are stained by 49,6-diamidino-2-phenylindole (DAPI). Immunofluorescence assay (IFA) validated the knockout in the Pfhmgb1-KO line.
Lu B, Liu M, Gu L, Li Y, Shen S, Guo G, Wang F, He X, Zhao Y, Shang X, Wang L, Yang G, Zhu Q, Cao J, Jiang C, Culleton R, Wei G, Zhang Q. The Architectural Factor HMGB1 Is Involved in Genome Organization in the Human Malaria Parasite Plasmodium falciparum. mBio. 2021 12(2):e00148-21.