PF3D7_1022700 phospholipid scramblase, plscr

PfPLSCR is expressed in gametocytes. A) Immunofluorescence analysis of stage III-IV gametocytes reveals different localisation patterns of the triple-HA tagged protein. Anti-Pfs16 is used as gametocyte specific antibody marking the PVM. Parasite nuclei are stained with DAPI. Scale bar = 1 mM. B) PfPLSCR-HA co-localises with the IMC marker GAP45, which delineates the parasite periphery.

Haase S, Condron M, Miller D, Cherkaoui D, Jordan S, Gulbis JM, Baum J. Identification and characterisation of a phospholipid scramblase in the malaria parasite Plasmodium falciparum. Mol Biochem Parasitol. 2021 8:111374

Other associated proteins

PFID Formal Annotation
PF3D7_0406200 parasitophorous vacuole membrane protein s16; sexual stage-specific protein s16
PF3D7_1222700 glideosome-associated protein 45