IFA images illustrating AMA1 protein stored in micronemes (top) or secreted and translocated at the surface of the parasite before egress (bottom). Middle: Magnified images of the areas indicated by a dashed box to the left. Microneme secretion was unaltered in Pfnd9 iKO parasites but rhoptry secretion was affected.
Aquilini E, Cova MM, Mageswaran SK, Dos Santos Pacheco N, Sparvoli D, Penarete-Vargas DM, Najm R, Graindorge A, Suarez C, Maynadier M, Berry-SterkersL, Urbach S, Fahy PR, Guérin AN, Striepen B, Dubremetz JF, Chang YW, Turkewitz AP, Lebrun M. An Alveolata secretory machinery adapted to parasite host cell invasion. Nat Microbiol. 2021 6(4):425-434.
Other associated proteins
|PF3D7_1133400||apical membrane antigen 1|