Immunofluorescence microscopy showing co-localisation of PfMSA180 with MSP-1 within mature schizonts. (a) Immunofluorescence detection of antibodies to C1 (N-terminus of PfMSA180) showing areas of co-localisation with MSP1 antibodies. Upper panel C1-PfMSA180 (Red), MSP1 (Green). Second panel C1-PfMSA180 (Green), Exp1 (Red). (b) Immunofluorescence detection of antibodies to C3 (C-terminus of PfMSA180) showing areas of co-localisation with MSP1 antibodies. Upper panel C3-PfMSA180 (Red), MSP1 (Green). Second panel C3-PfMSA180 (Green), Exp1 (Red). MSP1 is a merozoite surface protein and Exp1 (Exportin 1) is a parasitophorous vacuole membrane marker protein. The first column shows DAPI (4′,6-diamidino-2-phenylindole) DNA-stained schizonts, the second column shows the staining observed with marker antibodies, the third column displays PfMSA180 antibody staining, the fourth column is a merged image of the antibody staining, and the fifth column shows the transmitted image (TD) together with DAPI staining.
Bahl V, Chaddha K, Mian SY, Holder AA, Knuepfer E, Gaur D. Genetic disruption of Plasmodium falciparum Merozoite surface antigen 180 (PfMSA180) suggests an essential role during parasite egress from erythrocytes. Sci Rep. 2021 11(1):19183.
Other associated proteins
|PF3D7_1014100||merozoite surface protein msa180|
|PF3D7_1121600||parasitophorous vacuole membrane antigen QF 116 exported protein 1 circumsporozoite-related antigen|