Left: SEM image of a non-iRBC and additional SEM images of CS2, ΔPFA and
ΔPFA[PFA::HA]. Included is a display of aberrant eKnob morphologies. Right: IFA localisation of exported proteins. Investigation of marker protein localisation
using specific antisera in MeOH acetone-fixed ΔPFA with an IFA assay. No drastic difference in the localisation of EXP2, HSP70x, SBP1, REX2, PFEMP3, or PHISTC was found.
Diehl M, Roling L, Rohland L, Weber S, Cyrklaff M, Sanchez CP, Beretta CA, Simon CS, Guizetti J, Hahn J, Schulz N, Mayer MP, Przyborski JM. Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence. PLoS Pathog. 2021 Oct 6;17(10):e1009969.
PubMed Article: Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence
Other associated proteins
|PF3D7_0113700||heat shock protein 40, type II|
|PF3D7_0201900||erythrocyte membrane protein 3|
|PF3D7_0501300||skeleton-binding protein 1|
|PF3D7_0801000||Plasmodium exported protein PHISTc|
|PF3D7_0936000||ring-exported protein 2|
|PF3D7_1471100||exported protein 2|