PF3D7_1471100 exported protein 2

Left: SEM image of a non-iRBC and additional SEM images of CS2, ΔPFA and

ΔPFA[PFA::HA]. Included is a display of aberrant eKnob morphologies. Right: IFA localisation of exported proteins. Investigation of marker protein localisation

using specific antisera in MeOH acetone-fixed ΔPFA with an IFA assay. No drastic difference in the localisation of EXP2, HSP70x, SBP1, REX2, PFEMP3, or PHISTC was found.

Diehl M, Roling L, Rohland L, Weber S, Cyrklaff M, Sanchez CP, Beretta CA, Simon CS, Guizetti J, Hahn J, Schulz N, Mayer MP, Przyborski JM. Co-chaperone involvement in knob biogenesis implicates host-derived chaperones in malaria virulence. PLoS Pathog. 2021 Oct 6;17(10):e1009969.

Other associated proteins

PFID Formal Annotation
PF3D7_0113700 heat shock protein 40, type II
PF3D7_0201900 erythrocyte membrane protein 3
PF3D7_0501300 skeleton-binding protein 1
PF3D7_0801000 Plasmodium exported protein PHISTc
PF3D7_0831700 PfHsp70-x
PF3D7_0936000 ring-exported protein 2