PF3D7_0412100 ribosomal protein s12, mitochondrial, mtrps12

PfmtRPS12–3HA, PfmtRPS17–3HA, or PfmtRPS18–3HA are localized to the parasite mitochondrion. A co-staining of anti-HA antibody and MitoTracker is shown. Note that the tubular mitochondrion in trophozoites often becomes artificially “fragmented” after fixation with 4% paraform-aldehyde, 0.0075% glutar-aldehyde. Data shown are representatives of two independent IFA experiments. At least n=200 parasites were examined in each IFA experiment.

Ling L, Mulaka M, Munro J, Dass S, Mather MW, Riscoe MK, Llinás M, Zhou J, Ke H. Genetic ablation of the mitoribosome in the malaria parasite Plasmodium falciparum sensitizes it to antimalarials that target mitochondrial functions. J Biol Chem. 2020 295(21):7235-7248.

Other associated proteins

PFID Formal Annotation
PF3D7_1211500 ribosomal protein S18, mitochondrial
PF3D7_1365100 ribosomal protein s17, mitochondrial, mtrps17