PF3D7_1116800 heat shock protein 101 chaperone protein ClpB2

Brefeldin A treatment induces accumulation of HSP101 in the ER. (A) Representative IFA images of HSP101-HAglmS parasites treated with 0, 2, and 10 μM Brefeldin A (BFA) for 24 hours starting from the ring stage. Cells were fixed and stained with anti-HA (HSP101) and anti-ERC antibodies (ER marker). (C) Older ring stage parasites (16–20 hours post.

Gabriela M, Matthews KM, Boshoven C, Kouskousis B, Jonsdottir TK, Bullen HE, Modak J, Steer DL, Sleebs BE, Crabb BS, Koning-Ward TF, Gilson PR. A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell. PLoS Pathog. 2022 18(2):e1009977.

Other associated proteins

PFID Formal Annotation
PF3D7_1108600 endoplasmic reticulum-resident calcium binding protein
PF3D7_1436300 translocon component PTEX150
PF3D7_1471100 exported protein 2