GFP targeting by various P. falciparum redox proteins. (A) Apicoplast targeting of the AOP N-terminus. (B) Dual localization (cytosol and apicoplast) of the TPxGl N-terminal amino acid sequence. (C) ER-targeting of Trx3. (D) Mitochondrial targeting of Tlp2. (E) Mitochondrial targeting of GLP3. (F) Apicoplast targeting of the GILP N-terminal sequence. Colocalization of GFP with the mitochondrial dye MitoTrackerOrange in fixed cells. Colocalization of GFP and the apicoplast marker ACP or the ER marker BiP in fixed, immunodecorated cells.
Kehr S, Sturm N, Rahlfs S, Przyborski JM, Becker K. Compartmentation of redox metabolism in malaria parasites. PLoS Pathog. 2010 Dec 23;6(12):e1001242.
PubMed Article: Compartmentation of redox metabolism in malaria parasites
Other associated proteins
|PF3D7_0208500||acyl carrier protein|
|PF3D7_0604700||glyoxalase I-like protein gilp|
|PF3D7_0709200||Cg6 protein glutaredoxin-like protein|
|PF3D7_1212000||glutathione peroxidase-like thioredoxin peroxidase|