PF3D7_0925500 thioredoxin-like protein 2

GFP targeting by various P. falciparum redox proteins. (A) Apicoplast targeting of the AOP N-terminus. (B) Dual localization (cytosol and apicoplast) of the TPxGl N-terminal amino acid sequence. (C) ER-targeting of Trx3. (D) Mitochondrial targeting of Tlp2. (E) Mitochondrial targeting of GLP3. (F) Apicoplast targeting of the GILP N-terminal sequence. Colocalization of GFP with the mitochondrial dye MitoTrackerOrange in fixed cells. Colocalization of GFP and the apicoplast marker ACP or the ER marker BiP in fixed, immunodecorated cells.

Kehr S, Sturm N, Rahlfs S, Przyborski JM, Becker K. Compartmentation of redox metabolism in malaria parasites. PLoS Pathog. 2010 Dec 23;6(12):e1001242.

Other associated proteins

PFID Formal Annotation
PF3D7_0208500 acyl carrier protein
PF3D7_0604700 glyoxalase I-like protein gilp
PF3D7_0709200 Cg6 protein glutaredoxin-like protein
PF3D7_0729200 1-cys peroxiredoxin
PF3D7_0916100 thioredoxin 3
PF3D7_1212000 glutathione peroxidase-like thioredoxin peroxidase