PF3D7_0302500 cytoadherence linked asexual protein 3.1

Indirect immunofluorescence assays (IFAs) of indicated proteins in wild-type (WT) and transfected lines. In schizonts (top), CLAG3 colocalizes with RhopH3 in apical rhoptries (puncta) in 8-1HA but has a more diffuse distribution in 8-1HAtrunc. IFA with trophozoite-stage parasites (bottom) reveals a normal export of CLAG3 and colocalization with RhopH3 at the host membrane in 8-1HA but a reduced signal with failed export in 8-1HAtrunc. Scale bars, 5 mm

Shao J, Arora G, Manzella-Lapeira J, Brzostowski JA, Desai SA. Kinetic Tracking of Plasmodium falciparum Antigens on Infected Erythrocytes with a Novel Reporter of Protein Insertion and Surface Exposure. mBio. 2022 13(3):e0040422.

Other associated proteins

PFID Formal Annotation
PF3D7_0905400 high molecular weight rhoptry protein 3