Subcellular localization of PfHDP in PfHDP- GFP transgenic lines. The image shows PfHDP is trafficked in punctate vesicle- like structures in the parasite (B) The BODIPY- TR ceramide stain, which stains the lipid membranes shows PfHDP- GFP are trafficked to the parasite plasma membrane (C) PfHDP colocalizes with Hb, both inside the parasite as well as in the cytoplasm of erythrocyte (Pearson coefficient co- relation - 0.8)

Gupta P, Pandey R, Thakur V, Parveen S, Kaur I, Panda A, Bishi R, Mehrotra S, Akhtar A, Gupta D, Mohmmed A, Malhotra P. Heme Detoxification Protein (PfHDP) is essential for the hemoglobin uptake and metabolism in Plasmodium falciparum. FASEB Bioadv. 2022 Jul 12;4(10):662-674. doi: 10.1096/fba.2022-00021