CpAtg8, which does not functionally complement PfAtg8 function, correctly localizes to the apicoplast membrane. ) Representative live fluorescence images showing the localization of selected GFP-tagged PfAtg8 homologs. DNA was stained with Hoechst 33342. Maximum-intensity projections are shown. Bar, 5 μm. DIC, differential inference contrast.

Walczak M, Meister TR, Nguyen HM, Zhu Y, Besteiro S, Yeh E. Structure-Function Relationship for a Divergent Atg8 Protein Required for a Nonautophagic Function in Apicomplexan Parasites. mBio. 2023 Jan 10:e0364221. doi: 10.1128/mbio.03642-21. Epub ahead of print.