Subunit B accumulates at the DVM and colocalizes with other V- ATPase subunits. B- mCh cKO parasites were stained with Lysosensor Blue DND- 167 (LSB) or genetically engineered to express endogenous mNG- tagged proteins of interest. Shown are representative live fluorescence micrographs. A, C, D, and a: V- ATPase subunits; CRT: chloroquine resistance transporter; PM2: plasmepsin 2. (Scale bars, 5 µm.)

Alder A, Sanchez CP, Russell MRG, Collinson LM, Lanzer M, Blackman MJ, Gilberger TW, Matz JM. The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2306420120.