PF3D7_0731500 erythrocyte binding antigen-175

Colocalization studies of RALP1 with rhoptry and microneme marker proteins. (A and B) RALP1-C-specific antibodies (green) colocalize with the rhoptry protein RAP1 (red) (A) and predominantly colocalize with CLAG9 a rhoptry-specific marker, (red) (B) in fixed schizonts (s) and free merozoites (m) using RAP1- and CLAG9-specific antibodies, respectively. (C and D) RALP1-C-specific antibodies (green) visualize a different compartment within the parasite than the microneme marker proteins EBA-175 (red) (C) and EBA-181 (red) (D), as is evident in the merge of the two fluorescence photomicrographs. Nuclei were stained blue (DAPI).

Haase S, Cabrera A, Langer C, Treeck M, Struck N, Herrmann S, Jansen PW, Bruchhaus I, Bachmann A, Dias S, Cowman AF, Stunnenberg HG, Spielmann T, Gilberger TW. Characterization of a conserved rhoptry-associated leucine zipper-like protein in the malaria parasite Plasmodium falciparum. Infect Immun. 2008 76:879-87.

Other associated proteins

PFID Formal Annotation
PF3D7_0102500 erythrocyte binding antigen-181
PF3D7_0501600 rhoptry-associated protein 2
PF3D7_0722200 rhoptry-associated leucine zipper-like protein 1
PF3D7_0935800 cytoadherence linked asexual protein 9
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