PF3D7_0916100 thioredoxin 3

GFP targeting by various P. falciparum redox proteins. (A) Apicoplast targeting of the AOP N-terminus. (B) Dual localization (cytosol and apicoplast) of the TPxGl N-terminal amino acid sequence. (C) ER-targeting of Trx3. (D) Mitochondrial targeting of Tlp2. (E) Mitochondrial targeting of GLP3. (F) Apicoplast targeting of the GILP N-terminal sequence. Colocalization of GFP with the mitochondrial dye MitoTrackerOrange in fixed cells. Colocalization of GFP and the apicoplast marker ACP PFB0385w or the ER marker BiP PF11_0098 in fixed, immunodecorated cells.

Kehr S, Sturm N, Rahlfs S, Przyborski JM, Becker K. Compartmentation of redox metabolism in malaria parasites. PLoS Pathog. 2010 6:e1001242.

Other associated proteins

PFID Formal Annotation
PF3D7_0709200 Cg6 protein glutaredoxin-like protein
PF3D7_0729200 1-cys peroxiredoxin
PF3D7_0925500 thioredoxin-like protein 2
PF3D7_1212000 glutathione peroxidase-like thioredoxin peroxidase