PF3D7_1322100 set domain-containing protein 2

The protein encoded by the gene MAL13.P1.122 localize to the far nuclear periphery. MAL13P1.122 is a SET-domain protein (Histone-lysine N-methyltransferase), which localizes to the nuclear periphery surrounding the DAPI stained portion within the same region of CenPA (histone H3) and the histone mark H3K9m3. Co-localization studies by immunofluorescence. Nup100 (PFI0250c) and CenPA (histone H3 PF13_0185) are used as markers of the nuclear periphery.

Volz J, Carvalho TG, Ralph SA, Gilson P, Thompson J, Tonkin CJ, Langer C, Crabb BS, Cowman AF. Potential epigenetic regulatory proteins localise to distinct nuclear sub-compartments in Plasmodium falciparum. Int J Parasitol. 2010 40:109-21. Copyright Elsevier 2010.

Other associated proteins

PFID Formal Annotation
PF3D7_0905100 nucleoporin NUP221, putative
PF3D7_1333700 histone H3-like centromeric protein CSE4