GFP targeting by thioredoxin 2 in various stages of P. falciparum. (A) Early ring stage parasite showing Trx2-GFP targeting to the PV. (B) Early trophozoite stage parasite showing two fluorescent Trx2-GFP points lying directly under the parasite plasma membrane. (C) Late trophozoite/early schizont stage parasite showing numerous fluorescent Trx2-GFP points. (D) Schizont stage parasite showing numerous fluorescent Trx2-GFP points. (E) Schizont stage parasite showing a small number of observable fluorescent Trx2-GFP structures. Live cell imaging of erythrocytes infected with transgenic parasites.

Kehr S, Sturm N, Rahlfs S, Przyborski JM, Becker K. Compartmentation of redox metabolism in malaria parasites. PLoS Pathog. 2010 6:e1001242.