PF3D7_0827800 SET domain protein, putative

SET-domain proteins PF08_0012 and Histone-lysine N-methyltransferase PF13_0293 localize to the nuclear periphery marked by CenPA. (A) Localization of PF08_0012 reveals a clustered localization pattern present throughout the nuclear periphery of the cell. PF08_0012 is HA-tagged at the C-terminus and detected with anti-HA antibodies. (B) Live imaging of PF13_0293 shows localization to a distinct area in the nuclear periphery. Co-localization studies by immunofluorescence are shown. Nup100 (PFI0250c) and CenPA (histone H3 PF13_0185) are used as markers of the nuclear periphery.

Volz J, Carvalho TG, Ralph SA, Gilson P, Thompson J, Tonkin CJ, Langer C, Crabb BS, Cowman AF. Potential epigenetic regulatory proteins localise to distinct nuclear sub-compartments in Plasmodium falciparum. Int J Parasitol. 2010 40:109-21. Copyright Elsevier 2010.

Other associated proteins

PFID Formal Annotation
PF3D7_1355300 histone-lysine N-methyltransferase, putative