Immunoelectron micrographs of extracellular merozoites of P. falciparum. Merozoites were incubated with (A) mouse antiserum to bacterial lysates of clone C7, (B) mouse antiserum raised to E. coli containing the cloning vector pUC8 (negative control). Hsp70 is localized at the surface of the merozoite. The location of p75 on the merozoite surface is unusual for an hsp-related protein, as most of these are normally intracellular.
Reprinted by permission from Macmillan Publishers Ltd: Ardeshir F, Flint JE, Richman SJ, Reese RT. A 75 kd merozoite surface protein of Plasmodium falciparum which is related to the 70 kd heat-shock proteins. EMBO J. 1987 6:493-9. Copyright 2009. Copyright Elsevier 2011.