PF3D7_0816900 adenylate kinase 2

Localization of PfAK2. (A) Co-localization of PfAK2-GFP with serine-rich protein (SERA5). (B) A comparison the localization of PfAK2-GFP with Bodipy-TR-ceramide shows that the loops contain membranous material. (C) Co-localization of PfAK2-GFP with Plasmodium falciparum exported protein (Exp1) by using an anti-Exp1 antibody. Scale bar, 3 mm. PfAK2 localized to a ring-like structure around the 264 parasite, and ‘‘loops’’ apparently connected to the PVM. PfAK2-GFP co localizes with the PV resident protein SERA5 which seems to be excluded from the ‘‘loops’’ suggesting that PfAK2-GFP in actual fact associates with the membrane of the PV, rather than being found in a soluble state in the PV lumen.

Ma J, Rahlfs S, Jortzik E, Heiner Schirmer R, Przyborski J, Becker K. Subcellular localization of adenylate kinases in Plasmodium falciparum. FEBS Lett. 2012 Jul 17. [Epub ahead of print]

Other associated proteins

PFID Formal Annotation
PF3D7_0207600 serine repeat antigen 5
PF3D7_1121600 parasitophorous vacuole membrane antigen QF 116 exported protein 1 circumsporozoite-related antigen