PF3D7_1016300 glycophorin binding protein

GBP130 chimaeras localise to the endoplasmic reticulum in addition to the parasitophorous vacuole or erythrocyte cytosol. Images captured by immunofluorescence microscopy show substantial colocalisation of GBP130 chimaeras with the endoplasmic reticulum protein ERC PF11_0098 (upper panel). Intraparasitic fluorescence is also evident when chimaeras were colocalised with the parasitophorous vacuole membrane protein EXP-2 PF14_0678 (lower panel). Only the wild-type PEXEL chimaera is efficiently exported to the erythrocyte cytosol.

Boddey JA, Moritz RL, Simpson RJ, Cowman AF. Role of the Plasmodium export element in trafficking parasite proteins to the infected erythrocyte. Traffic. 2009 10:285-99. Copyright John Wiley & Sons Ltd. 2010.