PF3D7_1019900 autophagy-related protein 8

PfATG8 immunofluorescence staining throughout the erythrocytic cycle. Tightly synchronized P. falciparum D10-ACP-GFP parasites were immunolabeled with anti-PfATG8. D10 parasites express ACP-GFP, an apicoplast signal and transit peptide fused to GFP that localizes to the apicoplast. Localization of ACP-GFP and PfATG8 can be observed, although PfATG8 appears to surround the apicoplast, indicating a possible association with the outer membrane. Additional PfATG8 vesicles can be observed in the cytosol and host red blood cell from the late ring to late trophozoite stage, when parasites are metabolically active. DAPI is used as a DNA marker in blue. Scale bar: 5 μm.

Cervantes S, Bunnik EM, Saraf A, Conner CM, Escalante A, Sardiu ME, Ponts N,

Prudhomme J, Florens L, Le Roch KG. The multifunctional autophagy pathway in the human malaria parasite, Plasmodium falciparum.. Autophagy. 2013 Nov 11;10(1).

Other associated proteins

PFID Formal Annotation
PF3D7_0208500 acyl carrier protein
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