PF3D7_1037500 dynamin-like protein

PfDYN2 localizes to vesicle-like structures in parasites. IFA of schizont-infected erythrocyte using anti-PfDYN2 (green, a-c). Merged images of PfDYN2 (green) and the ER PfBIP PF11_0098 (red, d-f), the apicoplast PfACP PFB0385w (red, g-i) and the Golgi apparatus PfERD2 PF13_0280 (red, j-l). In blue, DAPI-stained DNA and in right panels, phase contrast images. Co-localizations are indicated by arrowheads and appear under orange-yellow color. Bar = 5 mm. PfDYN2 partly colocalized with markers of the parasite endoplasmic reticulum, Golgi apparatus and apicoplast, suggesting it could be implicated in vesicular trafficking and/or organelle fission events known to occur during the last hours of the parasite development in erythrocytes.

Charneau S, Bastos IM, Mouray E, Ribeiro BM, Santana JM, Grellier P, Florent I. Characterization of PfDYN2, a dynamin-like protein of Plasmodium falciparum expressed in schizonts. Microbes Infect. 2007 9:797-805.