PF3D7_1105000 histone H4

Combination of immunolocalization (antiacetylated H4 antibodies, green) and FISH (telomere, red) colocalization analysis of trophozoite-stage parasites. The nucleus is stained with DAPI. Acetylated H4 histone is excluded from the nuclear periphery.

Freitas-Junior LH, Hernandez-Rivas R, Ralph SA, Montiel-Condado D, Ruvalcaba-Salazar OK, Rojas-Meza AP, Mâncio-Silva L, Leal-Silvestre RJ, Gontijo AM, Shorte S, Scherf A. Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites. Cell. 2005 121:25-36. Copyright Elsevier 2009.