PF3D7_1203700 nucleosome assembly protein

Expression and activity of PfDTD. Localization of PfDTD in different intra-erythrocytic stages of P. falciparum by immunofluo-rescence staining, Ring stage (R), trophozoite stage (T), and schizont stage (S) are shown. In each panel are shown: (i) image of cell stained with DAPI (blue), (ii) anti-PfDTD antibodies, (iii) anti-PfNapL antibodies, (iv) merged image, (v) merge with phase contrast. Results clearly show the colocalization of PfDTD with PfNapL at all the asexual life stages of parasite, suggesting PfDTD to be cytoplasmic in nature, like for PfNapL.

Bhatt TK, Yogavel M, Wydau S, Berwal R, Sharma A. Ligand-bound structures provide atomic snapshots for the catalytic mechanism of D-amino acid deacylase. J Biol Chem. 2010 Feb 285(8):5917-30.

Other associated proteins

PFID Formal Annotation
PF3D7_1108200 D-tyrosyl-tRNA(Tyr) deacylase