PF3D7_1115700 cysteine proteinase falcipain 2a falcipain 2

Labeling of Fal2-S1 transfectants with BODIPY-TR ceramide at trophozoite stage. GFP fluorescence is seen overlapping with fluorescence by BODIPY-TR in the PV and food vacuole membrane. Some of the small foci having GFP fluorescence near PV (solid arrows), show overlap with fluorescence by BODIPY-TR. Some of these foci in panel IV are seen fused with the food vacuole (arrow head).

Dasaradhi PV, Korde R, Thompson JK, Tanwar C, Nag TC, Chauhan VS, Cowman AF, Mohmmed A, Malhotra P. Food vacuole targeting and trafficking of falcipain-2, an important cysteine protease of human malaria parasite Plasmodium falciparum. Mol Biochem Parasitol. 2007 156:12-23. Copyright Elsevier 2009.