Representative transmission electron microscopy with immunogold labeling (white arrows) of PfRON4 (the scale bar represents 0.2 mm). PfRON4 immunogold labeling was retained within the rhoptry neck preinvasion but significantly moved, in the majority to the cytosolic side of the erythrocyte membrane at the time of attachment (white arrows). Once inside, labeling could be seen to associate directly with the junction.

Riglar DT, Richard D, Wilson DW, Boyle MJ, Dekiwadia C, Turnbull L, Angrisano F, Marapana DS, Rogers KL, Whitchurch CB, Beeson JG, Cowman AF, Ralph SA, Baum J. Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte. Cell Host Microbe. 2011 9:9-20