PF3D7_1133400 apical membrane antigen 1

PTEX components are apically localised in merozoite dense granules. (A and B) Immunofluorescence assays were completed during schizogony and were probed for either PTEX components or markers of distinct organelles as indicated in each of the panels. (A) Merozoites probed with antibodies specific to both HSP101 and EXP2 demonstrate apical localization for both proteins. (B) Schizonts and merozoites were labeled with antibodies specific to HSP101 and either RESA (dense granules), AMA1 (micronemes) or RAP1 (rhoptries). Co-localisation quantitation reveals that HSP101 localises most closely with dense granule associated RESA (top two panels). Scale bar: 1μm.

Bullen HE, Charnaud SC, Kalanon M, Riglar DT, Dekiwadia C, Kangwanrangsan N, Torii M, Tsuboi T, Baum J, Ralph SA, Cowman AF, de Koning-Ward TF, Crabb BS, Gilson PR. Biosynthesis, localisation and macromolecular arrangement of the Plasmodium falciparum translocon of exported proteins; PTEX. J Biol Chem. 2012 287(11):7871-84.

Other associated proteins

PFID Formal Annotation
PF3D7_1116800 heat shock protein 101 chaperone protein ClpB2
PF3D7_1410400 rhoptry-associated protein 1
PF3D7_1471100 exported protein 2