PF3D7_0607300 uroporphyrinogen III decarboxylase

Localization of PfCPO by immunofluorescence microscopy. Localization of PfCPO with Mitotracker green (mitochondrial marker), PfALAS (mitochondrial marker) and PfUROD (apicoplast marker) was studied. IE, infected erythrocyte; P, parasite; H, hemozoin. Scale bar=5 μm. results presented in Fig. 4 indicate that the PfCPO signal was distributed throughout the parasite, but did not colocalize with that of Mitotracker dye (mitochondrial marker), PfALAS (mitochondrial marker) or PfUROD (apicoplast marker).

Nagaraj VA, Prasad D, Arumugam R, Rangarajan PN, Padmanaban G. Characterization of coproporphyrinogen III oxidase in Plasmodium falciparum cytosol. Parasitol Int. 2010 59:121-127. Copyright Elsevier 2011

Other associated proteins

PFID Formal Annotation
PF3D7_1142400 coproporphyrinogen-III oxidase HemF
PF3D7_1440300 delta-aminolevulinic acid dehydratase porphobilinogen synthase, HemB