Targeting of P. falciparum aminoacyl-tRNA synthetase and of DTD. The parasite line used was GFP-tagged (strain D10 ACPleader-GFP) where apicoplast fluorescence is in green. DAPI staining is in blue while aminoacyl-tRNA synthetases are stained with Alexa594 (red). only the late ring and early trophozoite-stage localizations are depicted here but patterns were identical in other intra-erythrocytic stages. All tRNA synthases were cytoplasmic except PFL1210w Ile which is seen located in the apicoplast and deacylase which is mitochondrial.
Khan S, Sharma A, Jamwal A, Sharma V, Pole AK, Thakur KK, Sharma A. Uneven spread of cis- and trans-editing aminoacyl-tRNA synthetase domains within translational compartments of P. falciparum. Sci Rep. 2011;1:188.
Other associated proteins
|PF3D7_1104000||phenylalanine--tRNA ligase beta subunit|
|PF3D7_1225100||isoleucine--tRNA ligase, putative|
|PF3D7_1332900||isoleucine--tRNA ligase, putative|
|PF3D7_1461900||valine--tRNA ligase, putative|