PF3D7_1220900 heterochromatin protein 1

Double staining immunofluorescence pictures obtained from the transgenic parasite line 3D7/HP1-HA expressing HA-tagged PfHP1. Cells were simultaneously probed with aHA and aPfCENH3 antibodies. PfCENH3 foci do not overlap with PfHP1-marked chromosome end clusters. GFP live fluorescence and aPfCENH3 6 antibody (green), aHA antibody (red), DAPI nuclear stain (blue), DIC (differential interference contrast). Scale bars are 5 μm long.

Hoeijmakers WA, Flueck C, Françoijs KJ, Smits AH, Wetzel J, Volz JC, Cowman AF, Voss T, Stunnenberg HG, Bártfai R. Plasmodium falciparum centromeres display a unique epigenetic makeup and cluster prior to and during schizogony. Cell Microbiol. 2012 14(9):1391-401.

Other associated proteins

PFID Formal Annotation
PF3D7_1333700 histone H3-like centromeric protein CSE4