PF3D7_1334500 MSP7-like protein

MSRP6 is a Maurer’s clefts protein expressed in trophozoites and schizonts. Pre-embedding immuno-EM of infected RBC, where the host cell cytosol has been released with tetanolysin, reacted with anti-MSRP6 antisera. Small panels show overviews with boxes highlighting individual Maurer’s clefts for which enlargements are shown. Gold label is indicated with arrowheads. Size bars: 1 mm. MSRP6 was detected in ‘cloudy’ structures at the outside of Maurer’s clefts. Lower panel: Co-localisation IFA using anti-REX1 and anti-MSRP6 antibodies with MSRP6 knock out parasites (top) and parental 3D7 parasites (bottom). Size bar: 5 mm. MSRP6 antiserum recognized foci in infected host cells representing Maurer’s clefts.

Heiber A, Kruse F, Pick C, Grüring C, Flemming S, Oberli A, Schoeler H, Retzlaff S, Mesén-Ramírez P, Hiss JA, Kadekoppala M, Hecht L, Holder AA, Gilberger TW, Spielmann T. Identification of New PNEPs Indicates a Substantial Non-PEXEL Exportome and Underpins Common Features in Plasmodium falciparum Protein Export. PLoS Pathog. 2013 9(8):e1003546

Other associated proteins

PFID Formal Annotation
PF3D7_0935900 ring-exported protein 1
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