Cellular localization of ECT in Plasmodium falciparum. Immunoflurorescence assays were done on human blood cells infected by P. falciparum 3D7 strain and revealed by anti-PfECT (red). Nuclei were stained in blue with DAPI. Differential interference contrast (DIC) images and merges are presented. The signal of the PfECT anti-sera was detected at all parasite stages showing a diffuse and dotted pattern. These data suggested that PfECT is present in the cytoplasm.

Maheshwari S, Lavigne M, Contet A, Alberge B, Pihan E, Kocken C, Wengelnik K, Douguet D, Vial H, Cerdan R. Biochemical characterization of Plasmodium falciparum CTP:phosphoethanolamine cytidylyltransferase shows that only one of the two cytidylyltransferase domains is active. Biochem J. 2012 450(1):159-67