PF3D7_1353200 membrane associated histidine-rich protein 2

MAHRP2 is associated with electron-dense tubules in the cytoplasm of infected erythrocytes. Thin sections through EqtII-permeabilized erythrocytes infected with 3D7 parasites. The sections were probed with rabbit anti-MAHRP2 antibody, and subsequently decorated with protein A-gold conjugate (6 nm). Maurer’s clefts (MC) have an electron-lucent lumen and an electron-dense coat. The structures labelled by MAHRP2 are slender electron-dense tubules (white arrows) that are often associated with the Maurer’s clefts. K, Knobs; RBCM, red blood cell membrane; PVM, PV membrane. Bars are 200 nm.

Pachlatko E, Rusch S, Müller A, Hemphill A, Tilley L, Hanssen E, Beck HP. MAHRP2, an exported protein of Plasmodium falciparum, is an essential component of Maurer's cleft tethers. Mol Microbiol. 2010 77(5):1136-52

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