PF3D7_0708400 heat shock protein 90

Immunofluorescence staining to detect Hsp40, HSP70, HSP90 and HOP was conducted on trophozoite stage P. falciparum-infected erythrocytes. Panels show from left to right a DIC image, distribution of protein of interest (POI), nuclear stain (Hoechst), merge and overlay (localization relative to the parasite nucleus and phase-contrast image). All proteins showed cytosolic localization.

Botha M, Chiang AN, Needham PG, Stephens LL, Hoppe HC, Külzer S, Przyborski JM, Lingelbach K, Wipf P, Brodsky JL, Shonhai A, Blatch GL. Plasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shock. Cell Stress Chaperones. 2011 16(4):389-401. Pictures were kindly provided by Jude Przyborski.

Other associated proteins

PFID Formal Annotation
PF3D7_0818900 PfHsp70-1
PF3D7_1434300 Hsp70/Hsp90 organizing protein
PF3D7_1437900 HSP40, subfamily A
img